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Distribution of serum anti-HBc levels in the natural history of CHB. Median values with 95% confidence interval (of median) represented. CHB = chronic hepatitis B, ENH = HBeAg-negative hepatitis, HBc = hepatitis B core antigen, HBeAg = hepatitis B early antigen, IC = immune clearance phase, IT = immune tolerance, LR = low replicative, PBI = past HBV infection.
