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Blood pressure changes during pregnancy according to maternal first-trimester biomarkers, in women followed at a public health center in Rio de Janeiro, Brazil, 2009 to 2012. (A) Alkaline phosphatase (ALP). (B) Alanine aminotransferase (ALT). (C) Creatinine (Cr). Left panels: systolic blood pressure; right panels: diastolic blood pressure. Note: Fitted values were predicted using a longitudinal linear regression model for each tertile of the first-trimester biomarkers.
