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HBeAg seroconversion and HBsAg clearance rates. HBeAg seroconversion (A) and HBsAg clearance (B) rates are shown for the PEG-IFN ST and PEG-IFN SOT groups at week 48, 24 weeks post-PEG-IFN treatment, and 120 weeks after PEG-IFN therapy initiation. HBeAg = hepatitis B virus e antigen, HBsAg = hepatitis B virus surface antigen, PEG-IFN SOT = pegylated interferon-α-2a stepwise optimization treatment, PEG-IFN ST = pegylated interferon-α-2a standard therapy, W, week.
