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PROX1 overexpression reduces CK18 and CK19 expression in SCC9 cell line. Immunoexpression of CK18 and 19 in SCC9 and SCC9 control (A and C) and in SCC9-PROX1 cell clones (B and D), respectively. SCC9 and SCC9-control cells showed an intense expression of CK18 (A) and CK19 (C) around the nucleus. SCC9-PROX1 cell clones revealed significantly reduced CK18 (B) and CK19 (D) protein expression compared with SCC9 and SCC9-control (P < 0.001)(E and F). PROX1 = prospero homeobox 1.
