Table 2. Crude and adjusted* mortality after multiple imputation, overall and by duration on ART.
| OVERALL | 0-12 months | 12-24 months | 24-36 months | ||
|---|---|---|---|---|---|
| HR | aHR*** | aHR | aHR | aHR | |
| Age (years) | |||||
| 16-29 | 1 | 1 | 1 | 1 | 1 |
| 30-34 | 1.06 (0.99-1.14) | 1.03 (0.96-1.10) | 1.05 (0.90-1.22) | 0.99 (0.73-1.35) | 0.83 (0.56-1.23) |
| 35-39 | 1.16 (1.08-1.24) | 1.12 (1.04-1.20) | 1.14 (0.99-1.32) | 1.11 (0.82-1.50) | 0.83 (0.57-1.22) |
| 40-44 | 1.29 (1.20-1.40) | 1.24 (1.14-1.34) | 1.26 (1.09-1.46) | 1.14 (0.84-1.55) | 0.78 (0.53-1.17) |
| 45-49 | 1.45 (1.33-1.58) | 1.35 (1.23-1.48) | 1.37 (1.17-1.60) | 1.39 (1.01-1.91) | 0.87 (0.57-1.32) |
| 50-54 | 1.73 (1. 57-1.92) | 1.65 (1.48-1.84) | 1.52 (1.28-1.80) | 1.63 (1.16-2.27) | 1.26 (0.82-1.93) |
| 55-59 | 1.94 (1.70-2.20) | 1.86 (1.63-2.14) | 1.89 (1.57-2.27) | 1.85 (1.30-2.66) | 1.87 (1.20-2.92) |
| 60-64 | 2.63 (2.19-3.16) | 2.49 (2.04-3.06) | 2.04 (1.63-2.54) | 1.77 (1.11-2.82) | 2.44 (1.45-4.10) |
| 65+ | 3.00 (2.43-3.70) | 2.52 (2.01-3.17) | 2.79 (2.21-3.53) | 3.21 (2.04-5.06) | 2.06 (1.07-3.98) |
| Male gender | 1.62 (1.55-1.70) | 1.40 (1.33-1.48) | 1.28 (1.19-1.37) | 1.38 (1.20-1.59) | 1.74 (1.45-2.10) |
| CD4+ cell count (cells/μL) | |||||
| <50 | 1 | 1 | 1 | 1 | 1 |
| 50-99 | 0.64 (0.60-0.68) | 0.71 (0.65-0.78) | 0.60 (0.55-0.65) | 0.82 (0.69-0.97) | 0.91 (0.72-1.17) |
| 100-199 | 0.39 (0.36-0.41) | 0.54 (0.80-0.59) | 0.40 (0.37-0.44) | 0.61 (0.52-0.72) | 0.85 (0.68-1.06) |
| 200-349 | 0.24 (0.22-0.26) | 0.38 (0.33-0.43) | 0.30 (0.26-0.35) | 0.53 (0.41-0.68) | 0.60 (0.42-0.86) |
| 350-499 | 0.34 (0.27-0.44) | 0.52 (0.41-0.65) | 0.43 (0.31-0.59) | 0.64 (0.34-1.22) | 1.25 (0.58-2.70) |
| ≥500 | 0.26 (0.18-0.37) | 0.44 (0.30-0.63) | 0.39 (0.25-0.62) | 0.40 (0.13-1.26) | 1.60 (0.59-4.31) |
| WHO stage | |||||
| I & II | 1 | 1 | 1 | 1 | 1 |
| III | 2.40 (2.18-2.65) | 1.64 (1.48-1.82) | 1.61 (1.34-1.93) | 1.70 (1.34-2.16) | 1.53 (1.12-2.08) |
| IV | 4.06 (3.66-4.51) | 2.37 (2.09-2.70) | 2.42 (1.98-2.97) | 2.15 (1.69-2.75) | 2.14 (1.52-3.02) |
| Anaemia | |||||
| none | 1 | 1 | 1 | 1 | 1 |
| mild | 1.76 (1.64-1.89) | 1.37 (1.25-1.50) | 1.51 (1.31-1.75) | 1.37 (1.10-1.71) | 1.33 (1.00-1.76) |
| moderate | 3.10 (2.87-3.35) | 1.99 (1.82-2.17) | 2.40 (2.05-2.81) | 1.77 (1.41-2.22) | 1.57 (1.14-2.15) |
| severe | 4.72 (4.00-5.56) | 2.92 (2.60-3.28) | 3.89 (3.35-4.52) | 2.03 (1.46-2.84) | 1.66 (1.04-2.64) |
| TB at enrolment | 1.53 (1.40-1.65) | 0.82 (0.76-0.90) | 0.81 (0.73-0.91) | 0.83 (0.66-1.04) | 0.92 (0.72-1.18) |
| Weight (kg) | 0.96 (0.96-0.96) | 0.98 (0.97-0.98) | 0.97 (0.97-0.98) | 0.98 (0.98-0.99) | 0.99 (0.99-0.99) |
*
also adjusted for site of ART initiation;
**
mortality corrected via linkage to the National Population Register;
***
aHR: adjusted Hazard Ratio