Table 1.
Group | Case # | Sex | Age (y) | Cause of death | PMI (h) | Hem | Brain weight (g) |
---|---|---|---|---|---|---|---|
Dup(15) | AN14762 | M | 9 | SUDEP | 13.6 | R | 1,130 |
autism | AN06365 | M | 10 | SUDEP | 17.7 | R | 1,070 |
AN09402 | M | 11 | SUDEP | 10.5 | R | 1,540 | |
AN07740 | F | 15 | SUDEP (suspected) | 24.0 | L | 1,141 | |
AN09470 | F | 15 | Pneumonia | — | L | 1,125 | |
AN07993 | F | 22 | SUDEP | 11.8 | L | 1,209 | |
AN05983 | M | 24 | SUDEP | 36.3 | L | 1,200 | |
AN14829 | F | 26 | SUDEP (suspected) | 28.6 | R | 1,310 | |
Mean ± SD | 16 ± 7 | 20.3 ± 9.6 | 1,215 ± 149 | ||||
Idiopathic autism | HSB4640 | M | 8 | Asthma attack | 13.8 | R | 1,740 |
AN01293 | M | 9 | SUDC | 3.7 | R | 1,690 | |
AN02736 | M | 15 | Pneumonia | 2.5 | L | 1,390 | |
AN01570 | F | 18 | SUDEP | 6.7 | L | 2,100 | |
IBR93-01 | M | 23 | Seizure-related | 14.0 | L | 1,610 | |
AN08166 | M | 28 | Seizure-related | 43.0 | R | 1,580 | |
NP06-54 | M | 32 | Glioblastomaa | — | L | 1,260 | |
AN06420 | M | 39 | Heart failure | 13.9 | R | 1,520 | |
Mean ± SD | 21 ± 11 | 14.0 ± 13.7 | 1,611 ± 251 | ||||
Control | UMB1706 | F | 8 | Cardiac transplant rejection | 20.0 | R | 1,340 |
UMB1670 | M | 14 | Asphyxia (hanging) | 5.0 | R | 1,420 | |
UMB4722 | M | 14 | Traumatic injuries | 16.0 | R | 1,340 | |
BTB-3960 | F | 25 | Not established | 26.0 | L | 1,520 | |
UMB4637 | F | 31 | Traumatic injuries | 17.0 | L | 1,354 | |
IBR291-00 | M | 32 | Heart failure | 14.0 | R | 1,401 | |
IBR212-98 | F | 33 | Bronchopneumonia | 6.0 | L | 1,260 | |
Mean ± SD | 22 ± 10 | 14.9 ± 7.4 | 1,376 ± 81 |
PMI post-mortem interval, Dup(15) chromosome 15q11.2-13.1 duplication syndrome, SUDEP sudden unexpected death in epilepsy, SUDC sudden unexplained death in childhood. Glioblastomaa was found as a single lesion located in the inferior temporal gyrus of the right hemisphere. Neoplastic changes were not detected in the left hemisphere examined morphometrically