Table 2.
Comparison of the serum cholesterol, LDL-C and non-HDL-C with MTTP genotypes
| Genotype | Cholesterol (mg/dl) | P | LDL (mg/dl) | P | Non-HDL (mg/dl) | P |
|---|---|---|---|---|---|---|
| (promoter) G-493T | ||||||
| GG+GT (n = 1159) | 180.7 ± 32.4 | 0.576 | 123.1 ± 33.1 | 0.391 | 129.3 ± 32.5 | 0.694 |
| TT (n = 29) | 184.1 ± 28.1 | 129.8 ± 29.7 | 132.3 ± 23.5 | |||
| Glu98Asp (E98D) | ||||||
| GG+GC (n = 1132) | 180.5 ± 31.9 | 0.551 | 123.2 ± 33.0 | 0.566 | 129.2 ± 32.3 | 0.719 |
| CC (n = 25) | 184.3 ± 28.5 | 127.7 ± 33.3 | 132.0 ± 2.7 | |||
| Iler128Thr (I128T) | ||||||
| TT+TC (n = 1153) | 180.6 ± 32.4 | 0.783 | 123.0 ± 33.1 | 0.384 | 129.3 ± 32.6 | 0.848 |
| CC (n = 26) | 182.4 ± 27.3 | 130.3 ± 31.6 | 130.9 ± 24.6 | |||
| Asn166Ser (N166S) | ||||||
| AA+AG (n = 1150) | 180.5 ± 32.2 | 0.489 | 122.9 ± 32.9 | 0.362 | 129.1 ± 32.4 | 0.543 |
| GG (n = 25) | 185.1 ± 29.2 | 130.1 ± 33.9 | 133.8 ± 27.9 | |||
| Gln297His (Q297H) | ||||||
| GG+GC (n = 984) | 180.9 ± 32.6 | 0.433 | 124.1 ± 33.7 | 0.047* | 129.9 ± 33.1 | 0.282 |
| CC (n = 193) | 179.0 ± 29.6 | 118.5 ± 28.8 | 126.6 ± 28.4 | |||
Data are shown as mean ± SD. Independent t test was used for statistical analysis. (* P < 0.05 indicates significant)