Table 5.
Risk impact and interaction of the MTTP genotypes on serum non-HDL-C
| Independent variables | Parameter estimates (B) | 95 % Confidence interval | P | |
|---|---|---|---|---|
| Lower vs Upper bound | ||||
| Age | 0.510 | 0.247 | 0.772 | <0.0001* |
| Sex (male vs female) | −9.122 | −43.247 | 25.035 | 0.6006 |
| BMI | 1.343 | 0.581 | 2.105 | 0.0011* |
| HOMA-IR | −4.397 | −6.606 | −2.189 | <0.0001* |
| Adipo-IR | 4.157 | 2.673 | 5.641 | <0.0001* |
| E98D (CC vs GG+GC) | −23.150 | −83.966 | 37.666 | 0.455 |
| I128T (CC vs TT+TC) | 6.400 | −12.309 | 25.110 | 0.502 |
| N166S (GG vs AA+AG) | 23.984 | −34.850 | 82.818 | 0.424 |
| Q297H (CC vs GG+GC) | −6.802 | −13.386 | −0.218 | 0.043* |
Multiple linear regression analysis was applied using serum non-HDL-C as dependent variable adjusted by age, sex, BMI, HOMA-IR, Adipo-IR and MTTP genotypes based on significance in univariate analysis and regression models. (*P < 0.05 indicates significant)