Table 6.
Risk impact and interaction of the MTTP genotypes on non-alcoholic fatty liver disease (NAFLD)
| Independent variables | Odds ratio (95 % confidence interval) | P |
|---|---|---|
| Age | 0.991 (0.973–1.009) | 0.313 |
| Sex | 1.252 (0.071–21.976) | 0.878 |
| BMI (kg/m2) | 1.370 (1.288–1.457) | <0.0001* |
| HOMA-IR | 0.895 (0.694–1.154) | 0.391 |
| Adipo-IR index | 1.266 (1.175–1.365) | <0.0001* |
| Promoter (TT vs GG+GT) | 0.588 (0.194–1.785) | 0.349 |
| E98D (CC vs GG+GC) | 0.711 (0.040–12.723) | 0.816 |
| N166S (GG vs AA+AG) | 1.028 (0.057–18.483) | 0.985 |
| Q297H (CC vs GG+GC) | 1.682 (1.102–2.568) | 0.016* |
Multiple logistic regression analysis was applied using NAFLD as a dependent variable adjusted by age, sex, BMI, HOMA-IR, Adipo-IR and MTTP genotypes based on significance in univariate analysis and regression models. (*P < 0.05 indicates significant)