Table 5.
Accuracy of CIMP prediction using gene expression profiles
| Accuracy | ||||
|---|---|---|---|---|
| Random | Lasso | Combined lasso | Group lasso | |
| Bladder | 62.8 | 62.9 (p = 1) | 74.2 (p≤2.10−16) | 72.1 (p≤2.10−16) |
| Breast | 80.5 | 83.9 (p≤2.10−16) | 84.7 (p≤2.10−16) | 85.5 (p≤2.10−16) |
| Colon | 79.4 | 79.5 (p = 1) | 95.0 (p≤2.10−16) | 94.2 (p≤2.10−16) |
| Lung | 73.2 | 84.2 (p≤2.10−16) | 76.2 (p≤2.10−16) | 86.6 (p≤2.10−16) |
| Stomach | 57.6 | 81.2 (p≤2.10−16) | 83.0 (p≤2.10−16) | 84.8 (p≤2.10−16) |
| Overall | 71.9 | 82.4 | 82.6 | 85.0 |
This table shows the accuracy, assessed by threefold cross-validation repeated 100 times over each tissue (first column), of sample classification in CIMP-positive and CIMP-negative classes from gene expression data using random classification (second column), lasso logistic regression (third column), combined lasso (fourth column), or group lasso logistic regression (fifth column)