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. 2015 Oct 12;15:672. doi: 10.1186/s12885-015-1693-z

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© Kala et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — Combination treatments did not alter epigenetic enzyme expression and their activity in MCF10A control cells. Overall DNMT enzyme activity analysis, using 20 μg of nuclear extract. After 72 h, there was no significant change in the enzyme activity in comparison to DMSO control in MCF10A control cells further highlighting the effectiveness of this combination regimen. Values are representative of three independent experiments and represented as percent of control ± SE; *P <0.05, **P <0.01