Table 2.
AKAP3 expression and clinico-pathologic data. Statistical association between clinico-pathologic data and AKAP3 expression in tumor and normal adjacent tissue
| Variable | AKAP3 expression | p value | AKAP3 expression | p value | ||
|---|---|---|---|---|---|---|
| In tumor | In normal | |||||
| Negative no (%) | Positive no (%) | Negative no (%) | Positive no (%) | |||
| ER | ||||||
| Negative | 27 (67.5) | 13 (32.5) | 0.4 | 21 (55.3) | 17 (44.7) | 0.5 |
| Positive | 20 (62.5) | 12 (37.5) | 17 (53.1) | 15 (46.9) | ||
| PR | ||||||
| Negative | 30 (63.8) | 17 (36.2) | 0.4 | 24 (53.3) | 21 (46.7) | 0.5 |
| Positive | 17 (68) | 8 (32) | 14 (56) | 11 (44) | ||
| Her2 | ||||||
| Negative | 34 (68) | 16 (32) | 0.3 | 25 (51) | 24 (49) | 0.2 |
| Positive | 13 (59.1) | 9 (40.9) | 13 (61.9) | 8 (38.1) | ||
| Tumor Grade | ||||||
| 1 | 3 (50) | 3 (50) | 0.7 | 3 (50) | 3 (50) | 0.9 |
| 2 | 21 (61.8) | 13 (38.2) | 18 (52.9) | 16 (47.1) | ||
| 3 | 18 (66.7) | 9 (33.3) | 14 (56) | 11 (44) | ||
| Lymph Node | ||||||
| No | 15 (68.2) | 7 (31.8) | 0.7 | 10 (45.5) | 12 (54.5) | 0.3 |
| 1-3 | 13 (56.5) | 10 (43.5) | 11 (47.8) | 12 (52.2) | ||
| 4-9 | 8 (57.1) | 6 (42.9) | 9 (75) | 3 (25) | ||
| >9 | 7 (70) | 3 (30) | 6 (60) | 4 (40) | ||
| Tumor size | ||||||
| ≤2cm | 10 (41.7) | 14 (58.3) | 0.01 | 13 (54.2) | 11 (45.8) | 0.5 |
| >2 cm | 32 (72.7) | 12 (27.3) | 23 (54.8) | 19 (45.2) | ||
| Stage | ||||||
| I | 1 (14.3) | 6 (85.7) | 0.04 | 2 (28.6) | 5 (71.4) | 0.2 |
| II | 22 (66.7) | 11 (33.3) | 16 (48.5) | 17 (51.5) | ||
| III | 14 (66.7) | 7 (33.3) | 12 (63.2) | 7 (36.8) | ||
| IV | 6 (75) | 2 (25) | 6 (75) | 2 (25) | ||
| Subtype | ||||||
| Triple Negative | 20 (80) | 5 (20) | 0.03 | 13 (54.2) | 11 (45.8) | 0.5 |
| Other types | 27 (56.3) | 21 (43.8) | 26 (55.3) | 21 (44.7) | ||
| Patient status | ||||||
| No event | 31 (63.3) | 18 (36.7) | 0.5 | 19 (41.3) | 27 (58.7) | 0.003 |
| With event | 14 (66.7) | 7 (33.3) | 16 (80) | 4 (20) | ||