Table 3.

Estimate of variation in presence of depressive symptoms and antidepressant medication use over time

	WHI-OS N = 68,169
	Antidepressant use at baseline	No antidepressant use at baseline
	N (%)	N (%)
Antidepressant use at year 3	3321 (4.9 %)	3083 (4.5 %)
No antidepressant use at year 3	1468 (2.2 %)	60297 (88.5 %)
	Presence of elevated symptoms at baseline	No presence of elevated symptoms at baseline
	N (%)	N (%)
Presence of elevated symptoms at year 3	4348 (6.4 %)	6333 (9.3 %)
No presence of elevated symptoms at year 3	5458 (8.0 %)	52030 (76.3 %)
	Baseline	Year 3
	Mean (SD)	Mean (SD)
BMI	26.80 (5.5)	27.09 (5.6)
	WHI-CT N = 52,326
	Antidepressant use at baseline	No antidepressant use at baseline
	N (%)	N (%)
Antidepressant use at year 3	2031 (3.9 %)	1979 (3.8 %)
No antidepressant use at year 3	1156 (2.2 %)	47160 (90.1 %)
	Baseline	Year 3
	Mean (SD)	Mean (SD)
BMI	28.54 (5.7)	28.78 (5.9)