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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Pediatr Clin North Am. 2015 Sep 7;62(6):1523–1529. doi: 10.1016/j.pcl.2015.07.013

Table I.

Characteristics of hepatic function and structure that may favor tolerance

Liver endothelial cells sample circulating antigen and act as APCs that lead to tolerance 45
Kupffer cells and conventional dendritic cells favor tolerance during antigen presentation 45
Plasmacytoid dendritic cells are abundant in the liver and support systemic tolerance 21