Table 2.

Cerium concentration at 28 days post-instillation of uncoated or silica-coated CeO₂ NPs

	CeO2	Silica-coated CeO2
	ng/g ± SE	ng/g ± SE
Lungs	136836.67 ± 4084.19	95193.25 ± 1766.39 *
Liver	59.35 ± 10.19	33.10 ± 2.78 *
Bone	38.13 ± 5.14	21.97 ± 2.87 *
Cecum	33.62 ± 10.95	24.15 ± 6.58
Large intestine	28.11 ± 8.94	24.33 ± 8.01
Bone marrow	16.55 ± 2.55	9.44 ± 1.05 *
Spleen	13.90 ± 6.21	3.83 ± 0.59
Stomach	12.77 ± 2.09	16.82 ± 8.64
Kidneys	10.40 ± 1.13	5.52 ± 0.35 *
Small intestine	10.14 ± 1.49	7.94 ± 2.20
Heart	1.95 ± 0.54	0.21 ± 0.08 *
Testes	0.54 ± 0.08	0.13 ± 0.04 *
Skeletal muscle	0.46 ± 0.21	0.20 ± 0.09
Brain	0.43 ± 0.24	0.15 ± 0.11
Skin	0.38 ± 0.08	0.16 ± 0.01 *
Plasma	0.14 ± 0.09	0.04 ± 0.04
RBC	0.04 ± 0.04	0.08 ± 0.06

Data are mean ± SE ng/g cerium concentration, n = 5/group

Ce concentration was estimated (ng/μCi_NPs x μCi/g_tissue)

*P < 0.05, CeO₂ vs. silica-coated CeO₂