Fig. 4.

The addition of JAK1i (0.5 μM) to cetuximab and radiation resulted in an enhancement of radiation-induced anti-proliferative (left) and apoptosis effects (right) in UM-SCC-1 cells. Cells were treated for 72 h with cetuximab (0.5 μM) with and without radiation (2 Gy) and subsequently assessed for cell proliferation or apoptosis as described in the methods section