Fig. 7.

The addition of cetuximab, JAK1i or the combination of cetuixmab and JAK1i prior to radiation did not enhance the number of radiation-induced DNA double strand breaks. UM-SCC-1 cells were treated with cetuximab (0.5 μg/ml) for one hour with and without JAK1i (1 μM) added 5 mins prior to radiation (2 Gy) and subsequently assessed for the mean tail moment as measured by the neutral comet assay and described in the methods section