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. 2015 Jul 29;6(9):966–971. doi: 10.1021/acsmedchemlett.5b00014

Figure 1.

Figure 1

Neuroprotective hit compound, IBS141, has an incorrect structure annotation. (a) Overview of high-throughput screen used to identify IBS141. Reported structure of IBS141 in the vendor database. Viability dose–response curve of IBS141 in PC12 mHTT-Q103 cells. (b) Viability dose–response curve and proton NMR spectra of IBS141 and CBG141. CBG141 is a compound with the same annotated structure as IBS141 but from a different chemical supplier. All viability data represent the average of triplicates ± SD (n = 3) and plotted as percent of DMSO treated uninduced cells.