TABLE 1.
Characteristics of the fresh, nondonor elective single ET compared with all other fresh, nondonor transfers—United States, 1999–2010.
| Characteristic | Elective single ET (%) | All others (%) |
|---|---|---|
| Total | 17,166 (100) | 869,520 (100) |
| Maternal age, ya | ||
| <30 | 3,821 (22.2) | 108,689 (12.5) |
| 30–34 | 8,406 (49.0) | 281,923 (32.4) |
| 35–37 | 3,599 (21.0) | 198,192 (22.8) |
| 38–40 | 1,097 (6.4) | 172,089 (19.8) |
| ≥41 | 243 (1.4) | 108,627 (12.5) |
| Race/ethnicitya | ||
| Non-Hispanic white | 7,731 (45.0) | 392,460 (45.1) |
| Non-Hispanic black | 600 (3.5) | 31,213 (3.6) |
| Hispanic | 1,454 (8.5) | 47,024 (5.4) |
| Asian/Pacific Islander | 626 (3.7) | 38,574 (4.4) |
| Other race | 28 (0.2) | 923 (0.1) |
| Unknown or missing | 6,727 (39.2) | 359,326 (41.3) |
| Infertility diagnosisa,b | ||
| Tubal factor | 2,950 (17.2) | 185,540 (21.3) |
| Endometriosis | 1,706 (10.0) | 123,789 (14.2) |
| Uterine factor | 1,004 (5.9) | 44,193 (5.1) |
| Ovulatory disorder | 3,717 (21.7) | 122,997 (14.2) |
| Diminished ovarian reserve | 953 (5.6) | 142,034 (16.3) |
| Male factor | 6,143 (35.8) | 329,417 (37.9) |
| Unexplained | 2,620 (15.3) | 107,924 (12.4) |
| No. of prior pregnancies | ||
| 0 | 8,113 (47.4) | 409,625 (47.2) |
| 1 | 4,547 (26.5) | 226,411 (26.1) |
| ≥2 | 4,472 (26.1) | 232,140 (26.7) |
| No. of prior spontaneous abortionsa | ||
| 0 | 12,943 (75.4) | 603,721 (69.5) |
| 1 | 2,864 (16.7) | 169,080 (19.5) |
| ≥2 | 1,356 (7.9) | 95,783 (11.0) |
| No. of prior live birthsa | ||
| 0 | 11,156 (65.5) | 628,104 (72.6) |
| 1 | 4,325 (25.4) | 174,947 (20.2) |
| ≥2 | 1,548 (9.1) | 61,680 (7.1) |
| No. of prior ART cyclesa | ||
| 0 | 12,882 (75.0) | 486,083 (55.9) |
| 1 | 2,068 (12.1) | 177,067 (20.4) |
| ≥2 | 2,216 (12.9) | 205,832 (23.7) |
| Year cycle treatment starteda | ||
| 1999–2004 (first guidelines September 2004) | 1,597 (9.3) | 393,050 (45.2) |
| 2005–2010 | 15,569 (90.7) | 476,470 (54.8) |
| Insurance mandate statusa | ||
| State not providing coverage for ART | 5,830 (36.1) | 311,713 (39.0) |
| State providing coverage | 10,312 (63.9) | 487,996 (61.0) |
| No. of oocytes retrieveda | ||
| 1–10 | 3,523 (20.5) | 406,726 (46.8) |
| 11–15 | 4,391 (25.6) | 217,602 (25.0) |
| ≥16 | 9,252 (53.9) | 245,192 (28.2) |
| Use of intracytoplasmic sperm injection (ICSI)a | ||
| Did not use ICSI | 5,946 (34.7) | 287,588 (33.1) |
| Used ICSI | 11,201 (65.3) | 581,551 (66.9) |
| With male factor | 5,625 (50.2)c | 280,366 (48.2)c |
| Without male factor | 5,576 (49.8)c | 301,185 (51.8)c |
| Use of assisted hatchinga | ||
| Did not use assisted hatching | 14,124 (82.3) | 477,975 (55.0) |
| Used assisted hatching | 3,042 (17.7) | 391,545 (45.0) |
| Use of preimplantation genetic diagnosis (PGD)a,d | ||
| Did not use PGD | 14,491 (91.4) | 496,167 (95.4) |
| Used PGD | 1,356 (8.6) | 23,857 (4.6) |
| Missing | 1,319 | 349,496 |
| Embryo stage at transfera | ||
| Cleavage stage (day 3) | 2,667 (22.0) | 537,074 (74.6) |
| Blastocyst stage (day 5) | 9,476 (78.0) | 182,554 (25.4) |
| Missing/out of range | 5,023 | 149,892 |
| No. of embryos transferreda | ||
| 1 | 17,166 (100) | 70,024 (8.0) |
| 2 | 0 | 364,723 (42.0) |
| ≥3 | 0 | 434,773 (50.0) |
| No. of supernumerary embryos cryopreserveda | ||
| Unknown | 0 | 4,226 (0.5) |
| 0 | 0 | 594,623 (68.4) |
| ≥1 | 17,166 (100) | 270,671 (31.1) |
Note: ART = assisted reproductive technology.
a
P<.001 for χ2 test of distribution of variable in the elective single ET group versus all other transfers.
b
percentages do not sum to 100 because groups are not mutually exclusive (patient may carry multiple diagnoses).
c
Among those using ICSI.
d
Data only available for 2004 and later.
Steinberg. Elective single ET trends and outcome predictors. Fertil Steril 2013.