TABLE 1.
Characteristic | Elective single ET (%) | All others (%) |
---|---|---|
Total | 17,166 (100) | 869,520 (100) |
Maternal age, ya | ||
<30 | 3,821 (22.2) | 108,689 (12.5) |
30–34 | 8,406 (49.0) | 281,923 (32.4) |
35–37 | 3,599 (21.0) | 198,192 (22.8) |
38–40 | 1,097 (6.4) | 172,089 (19.8) |
≥41 | 243 (1.4) | 108,627 (12.5) |
Race/ethnicitya | ||
Non-Hispanic white | 7,731 (45.0) | 392,460 (45.1) |
Non-Hispanic black | 600 (3.5) | 31,213 (3.6) |
Hispanic | 1,454 (8.5) | 47,024 (5.4) |
Asian/Pacific Islander | 626 (3.7) | 38,574 (4.4) |
Other race | 28 (0.2) | 923 (0.1) |
Unknown or missing | 6,727 (39.2) | 359,326 (41.3) |
Infertility diagnosisa,b | ||
Tubal factor | 2,950 (17.2) | 185,540 (21.3) |
Endometriosis | 1,706 (10.0) | 123,789 (14.2) |
Uterine factor | 1,004 (5.9) | 44,193 (5.1) |
Ovulatory disorder | 3,717 (21.7) | 122,997 (14.2) |
Diminished ovarian reserve | 953 (5.6) | 142,034 (16.3) |
Male factor | 6,143 (35.8) | 329,417 (37.9) |
Unexplained | 2,620 (15.3) | 107,924 (12.4) |
No. of prior pregnancies | ||
0 | 8,113 (47.4) | 409,625 (47.2) |
1 | 4,547 (26.5) | 226,411 (26.1) |
≥2 | 4,472 (26.1) | 232,140 (26.7) |
No. of prior spontaneous abortionsa | ||
0 | 12,943 (75.4) | 603,721 (69.5) |
1 | 2,864 (16.7) | 169,080 (19.5) |
≥2 | 1,356 (7.9) | 95,783 (11.0) |
No. of prior live birthsa | ||
0 | 11,156 (65.5) | 628,104 (72.6) |
1 | 4,325 (25.4) | 174,947 (20.2) |
≥2 | 1,548 (9.1) | 61,680 (7.1) |
No. of prior ART cyclesa | ||
0 | 12,882 (75.0) | 486,083 (55.9) |
1 | 2,068 (12.1) | 177,067 (20.4) |
≥2 | 2,216 (12.9) | 205,832 (23.7) |
Year cycle treatment starteda | ||
1999–2004 (first guidelines September 2004) | 1,597 (9.3) | 393,050 (45.2) |
2005–2010 | 15,569 (90.7) | 476,470 (54.8) |
Insurance mandate statusa | ||
State not providing coverage for ART | 5,830 (36.1) | 311,713 (39.0) |
State providing coverage | 10,312 (63.9) | 487,996 (61.0) |
No. of oocytes retrieveda | ||
1–10 | 3,523 (20.5) | 406,726 (46.8) |
11–15 | 4,391 (25.6) | 217,602 (25.0) |
≥16 | 9,252 (53.9) | 245,192 (28.2) |
Use of intracytoplasmic sperm injection (ICSI)a | ||
Did not use ICSI | 5,946 (34.7) | 287,588 (33.1) |
Used ICSI | 11,201 (65.3) | 581,551 (66.9) |
With male factor | 5,625 (50.2)c | 280,366 (48.2)c |
Without male factor | 5,576 (49.8)c | 301,185 (51.8)c |
Use of assisted hatchinga | ||
Did not use assisted hatching | 14,124 (82.3) | 477,975 (55.0) |
Used assisted hatching | 3,042 (17.7) | 391,545 (45.0) |
Use of preimplantation genetic diagnosis (PGD)a,d | ||
Did not use PGD | 14,491 (91.4) | 496,167 (95.4) |
Used PGD | 1,356 (8.6) | 23,857 (4.6) |
Missing | 1,319 | 349,496 |
Embryo stage at transfera | ||
Cleavage stage (day 3) | 2,667 (22.0) | 537,074 (74.6) |
Blastocyst stage (day 5) | 9,476 (78.0) | 182,554 (25.4) |
Missing/out of range | 5,023 | 149,892 |
No. of embryos transferreda | ||
1 | 17,166 (100) | 70,024 (8.0) |
2 | 0 | 364,723 (42.0) |
≥3 | 0 | 434,773 (50.0) |
No. of supernumerary embryos cryopreserveda | ||
Unknown | 0 | 4,226 (0.5) |
0 | 0 | 594,623 (68.4) |
≥1 | 17,166 (100) | 270,671 (31.1) |
Note: ART = assisted reproductive technology.
P<.001 for χ2 test of distribution of variable in the elective single ET group versus all other transfers.
percentages do not sum to 100 because groups are not mutually exclusive (patient may carry multiple diagnoses).
Among those using ICSI.
Data only available for 2004 and later.
Steinberg. Elective single ET trends and outcome predictors. Fertil Steril 2013.