Table 2.
Outcomes of assessable patients with pancreatic cancer according to protein expression
Variable | Overall survival | Disease-free survival | ||||
---|---|---|---|---|---|---|
HR | 95 % CI | P | HR | 95 % CI | P | |
LC3 | ||||||
Low (n = 50) | 1 | 0.087–0.589 | 0.200 | 1 | 0.251–1.387 | 0.226 |
High (n = 43) | 0.227 | 0.590 | ||||
ALDH1 | ||||||
Low (n = 51) | 1 | 0.516–3.684 | 0.522 | 1 | 0.315–1.481 | 0.335 |
High (n = 42) | 1.378 | 0.684 | ||||
LC3/ALDH1 | ||||||
Low (n = 54) | 1 | 1.622–13.739 | 0.004 | 1 | 2.535–17.170 | 0.000 |
High (n = 39) | 4.721 | 6.597 | ||||
OPN | ||||||
Low (n = 58) | 1 | 0.233–2.430 | 0.634 | 1 | 0.442–4.234 | 0.587 |
High (n = 35) | 0.752 | 1.368 | ||||
OPN/LC3/ALDH1 | ||||||
Low (n = 42) | 1 | Reference | 1 | Reference | ||
Moderate (n = 28) | 1.770 | 0.846–3.704 | 0.130 | 1.351 | 0.773–2.362 | 0.291 |
High (n = 23) | 2.385 | 1.129–5.038 | 0.023 | 2.245 | 1.183–4.259 | 0.013 |
OPN/CD44/CD133 | ||||||
Low (n = 39) | 1 | Reference | 1 | Reference | ||
Moderate (n = 42) | 1.929 | 0.897–4.146 | 0.093 | 1.639 | 0.889–3.021 | 0.113 |
High (n = 12) | 4.527 | 1.403–14.604 | 0.011 | 4.140 | 1.672–10.254 | 0.002 |
The bold value indicates P < 0.05