Table 1.
Effect of genotype on VEP latency and amplitude in naive PN75 Npc1 +/+ and Npc1 −/− micea
| Npc1 +/+ (n = 12) | Npc1 −/− (n = 12) | t | (df) b | p c | |
|---|---|---|---|---|---|
| Latency, N1 | 27.59 ± 0.16d | 28.98 ± 0.59 | 2.29 | (22) | 0.0396 |
| Latency, N2 | 35.08 ± 0.62 | 37.35 ± 0.55 | 2.75 | (22) | 0.0118 |
| Latency, N3 | 43.37 ± 0.81 | 44.70 ± 0.85 | 1.14 | (22) | 0.2778 |
| Amplitude, N1 | 105.20 ± 13.67 | 22.00 ± 6.32 | 5.52 | (22) | 0.0001 |
aThe mice examined in this experiment did not receive any kind of experimental manipulation before electrode implants and VEP recording
bDegree of freedom
c p was evaluated by unpaired two-tailed Student’s t test
dmean ± SEM