Table 3.
Mutational events and their consequences for TCS gene sets
| Apparent mutational event | Within-genus frequency (%) | Within-family frequency (%) | Typical consequences |
|---|---|---|---|
| Chromosomal Rearrangements | ~1-2 % | ~3 % | Gene gain/loss. |
| Large (≥1 gene) indels | ~10 % | ~20 | Gene gain/loss, with occasional changes in gene organisation (in ~10 % of cases). |
| - Duplications | <<1 % | ~3 % | Gene gain. |
| - Horizontal transfer | ~2 % | ~4 % | Gene gain. |
| Small (<1 gene) indels | ~1-2 % | ~3 % | Domain gain/loss, changes in family. |
| - Frameshifts | <1 % | ~1 % | Change in family (often through changes in RR output domains), pseudogene formation. |
Percentages of orthologous clusters which show evidence of evolutionary changes when comparing genomes from the same genus (within-genus) and the same family (within-family). Percentages obtained from pairwise comparisons between Cystobacterineae members