Table 1.

Time points of each assessment index

Week	Screening (baseline)	1		2		3		4		5	7	9	12
Visit	1	2	3	4	5	6	7	8	9	10	11	12	13
Informed consent	o
Demographic characteristics, Medical history	o
Inclusion/Exclusion criteria	o
Blood test	o									o			o
MRI	o												o
Credibility and Expectancy Questionnaire	o
Blinding test				o
Randomization		o
Treatment		o	o	o	o	o	o	o	o
Education program		o		o		o		o		o	o	o	o
NRS	o	o	o	o	o	o	o	o	o	o	o	o	o
VAS		o		o		o		o		o	o	o	o
ODI		o		o		o		o		o	o	o	o
Physical examination		o		o		o		o		o	o	o	o
SF-36		o								o	o		o
EQ-5D		o								o	o		o
PGIC										o	o		o
Safety assessment		o	o	o	o	o	o	o	o	o	o	o	o
Use of medication		o	o	o	o	o	o	o	o	o	o	o	o

EQ-5D EuroQol-5 Dimension, MRI magnetic resonance imaging, ODI Oswestry Disability Index, NRS, Numeric Rating Scale, PGIC patient global impression of change, SF-36 Short Form Health Survey 36, VAS Visual Analog Scale