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. Author manuscript; available in PMC: 2015 Oct 13.
Published in final edited form as: Cell Res. 2009 Feb;19(2):208–215. doi: 10.1038/cr.2008.320

Figure 3.

Figure 3

IL-17RD mediates IL-17 signaling. MEFs were transfected with 24p3 native promoter-luciferase reporter and IL-17RD and/or IL-17R (A) or multiple doses of IL-17RD (B) or wild-type and mutant IL-17RD (C) or multiple doses of IL-17RD-ΔICD (D) or IL-17RDΔICD and/or IL-17R (E) plasmids as indicated. After 24 h, cells were stimulated with (+IL-17) or without (−IL-17) 100 ng/ml IL-17 for 8 h and then luciferase activity was analyzed using the Dual-Luciferase Reporter Assay System. Data were normalized by co-transfection with a Renilla reniformis luciferase reporter vector. Results presented are from one experiment assayed in triplicate. Similar results were obtained in three independent experiments.

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