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. 2015 Oct 12;34:118. doi: 10.1186/s13046-015-0238-2

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© Xiang et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Tivantinib induces apoptosis of MHCC97L and Huh7 cells though the intrinsic and extrinsic pathway. a MHCC97L and Huh7 cells were treated with tivantinib for 48 h, and then stained with Annexin V–FITC and propidium iodide (PI) for flow cytometric analysis. Data were analyzed using Kaluza software and were reported as the mean ± SD. b Changes of the expression of apoptosis related proteins in MHCC97L and Huh7 cells treated with tivantinib for 48 h. *, P < 0.05 vs. the control group