Fig 1. (A) Prevalence of reporting of randomisation, blinded assessment of outcome, sample size calculation, and conflict of interest in 146 publications describing in vivo research identified through random sampling from PubMed; change in prevalence of (B) randomisation, (C) blinded assessment of outcome, and (D) conflict of interest reporting in quintiles of year of publication.
Vertical error bars represent the 95% confidence intervals of the estimates (S1 Data).