Table 2.
Taqman genotyping (rs725605-CA1) result (control n = 288)
| SNP identity-gene | Breast cancer n = 278 | Rectal carcinoma n = 132 | Colon carcinoma n = 140 | Cervical carcinoma n = 179 | Esophageal carcinoma n = 259 | Gastric carcinoma n = 263 | Liver cancer n = 186 | Lung carcinoma n = 181 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Allele | A | G | A | G | A | G | A | G | A | G | A | G | A | G | A | G |
| Case (freq) | 220 (0.396) | 118 (0.447) | 113 (0.404) | 163 (0.455) | 252 (0.486) | 232 (0.441) | 162 (0.435) | 174 (0.481) | ||||||||
| 336 (0.604) | 146 (0.553) | 167 (0.596) | 195 (0.545) | 266 (0.514) | 294 (0.559) | 210 (0.565) | 188 (0.519) | |||||||||
| Control (freq) | 270 (0.475) | 270 (0.475) | 270 (0.475) | 270 (0.475) | 270 (0.475) | 270 (0.475) | 270 (0.475) | 270 (0.475) | ||||||||
| 298 (0.525) | 298 (0.525) | 298 (0.525) | 298 (0.525) | 298 (0.525) | 298 (0.525) | 298 (0.525) | 298 (0.525) | |||||||||
| Odds Ratio (% 95 CI) | 0.722663 | 0.892034 | 0.746817 | 0.922583 | 1.045614 | 0.870950 | 0.851429 | 1.021513 | ||||||||
| (0.570361~0.915634) | (0.665320~1.196004) | (0.558798~0.998101) | (0.707594~1.202893) | (0.823876~1.327031) | (0.686340~1.105216) | (0.654582~1.107471) | (0.784591~1.329979) | |||||||||
| Fisher’s p value | 0.0071 | 0.44502 | 0.0483 | 0.55165 | 0.714 | 0.255551 | 0.230431 | 0.874386 | ||||||||
| Genotype | A/A | A/A | A/A | A/A | A/A | A/A | A/A | A/A | ||||||||
| A/G | A/G | A/G | A/G | A/G | A/G | A/G | A/G | |||||||||
| G/G | G/G | G/G | G/G | G/G | G/G | G/G | G/G | |||||||||
| Case (freq) | 49 (0.176) | 23 (0.174) | 21 (0.150) | 38 (0.212) | 51 (0.197) | 53 (0.202) | 33 (0.177) | 41 (0.227) | ||||||||
| 122 (0.439) | 72 (0.545) | 71 (0.507) | 87 (0.486) | 150 (0.579) | 126 (0.479) | 96 (0.516) | 92 (0.508) | |||||||||
| 107 (0.385) | 37 (0.280) | 48 (0.343) | 54 (0.302) | 58 (0.224) | 84 (0.319) | 57 (0.306) | 48 (0.265) | |||||||||
| Control (freq) | 67 (0.236) | 67 (0.236) | 67 (0.236) | 67 (0.236) | 67 (0.236) | 67 (0.236) | 67 (0.236) | 67 (0.236) | ||||||||
| 136 (0.479) | 136 (0.479) | 136 (0.479) | 136 (0.479) | 136 (0.479) | 136 (0.479) | 136 (0.479) | 136 (0.479) | |||||||||
| 81 (0.285) | 81 (0.285) | 81 (0.285) | 81 (0.285) | 81 (0.285) | 81 (0.285) | 81 (0.285) | 81 (0.285) | |||||||||
| Fisher’s p value | 0.029 | 0.30265 | 0.1048 | 0.825315 | 0.063 | 0.53125 | 0.317314 | 0.820064 | ||||||||
| HWE for case (df = 1) | 0.1697 | 0.23526 | 0.527 | 0.787951 | 0.01 | 0.645998 | 0.497597 | 0.807632 | ||||||||
| HWE for control (df = 1) | 0.5011 | 0.50114 | 0.5011 | 0.501122 | 0.501 | 0.501136 | 0.501122 | 0.501122 | ||||||||