Table 4.
Summary of molecular histotype results for 22 cases of mixed epithelial ovarian cancer.
Histotypes based on morphological review* | Pure histotype based on molecular studies (# of cases) | Type of pure EOC | Mixed based on molecular studies (# of cases) | Histotypes in mixed EOC by molecular studies |
---|---|---|---|---|
EC/CCC (n=9) | 3 | CCC (n=2) | 6 | EC/CCC (n=6) |
EC(n=1) | ||||
EC/LGSC/SBT (n=4) | 2 | HGSC(n=1) | 2 | EC/CCC (n=1) |
EC(n=1) | EC/LGSC (n=1) | |||
HGSC/CC (n=3) | 1 | HGSC (n=1) | 2 | HGSC/CCC (n=2) |
CCC/MC (n=2) | 1 | CCC (n=1) | 1 | CCC/MC (n=1) |
MC/SBT (n=1) | 1 | EC(n=1) | 0 | - |
CCC/SMBT/EC (n=1) | 1 | EC (n=1) | 0 | - |
MC/Brenner BT (n=1) | 0 | - | 1 | CCC/MC (n=1) |
MC/HGSC (n=1) | 0 | - | 1 | MC/HGSC (n=1) |
Total: 22 cases | Total: 9 (41%) | Total mixed based on molecular studies: 13 (59%) | Morphology concordant with molecular results in 11/13 mixed cases (85%) |
SMBT: seromucinous tumor; Brenner BT: brenner borderline tumor