Table 4.

Impact of acute GVHD and chronic GVHD on disease progression

	CR1/CR2 N=164			Non-CR1/CR2 N=101
	HR	95% CI	P	HR	95% CI	P
History of aGVHD II-IV	1.7	0.8-3.6	0.2	0.5	0.2-1.2	0.1
History of aGVHD III-IV	No Events*		0.3	1.2	0.3-5.0	0.8
cGVHD (as time-dependent variable)	0.3	0.1-0.8	0.02	0.6	0.3-1.3	0.2

Bivariate analysis cGVHD and T-lymphocyte chimerism	HR	95% CI	P	HR	95% CI	P
cGVHD (as time-dependent variable)	0.3	0.1-0.8	0.02	0.6	0.3-1.3	0.2
Chimerism ≤ 85%	2.2	1.1-4.6	0.03	1.2	0.5-2.9	0.6

^*No events in 2 patients with grade III-IV aGVHD