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. 2015 Oct 13;10(10):e0140476. doi: 10.1371/journal.pone.0140476

Table 2. Comparison of different stable transgenic expression systems for the production of 2G12 mAB in plants.

Species Tag Organ Promoter Yield Reference
Tobacco - Leaf CaMV 35S 17–18 μg/mL (45 μg/g)* [37]
KDEL KDELELP, KDEL leafseedLeaf CaMV 35S Faba bean USPCaMV 35S 0.4% of TSP0,3% of TSP1% of TSP (2.8 μg/g)**(1.7 μg/g)**(6.9 μg/g)** [11][11][11]
ELP, KDEL Seed Faba bean USP 1% of TSP (5.8 μg/g)** [11]
Maize KDEL- Kernels/ endospermKernels/ endosperm Rice Glut1Rice Glut1 30 μg/g75 μg/g [5][6]
Rice - Kernels/ endosperm Rice Glut1 46 μg/g [33]
Barley KDEL Grain/ endosperm Oat Glo1 0.4% of TSP (160 μg/g) this study

* line selected over several generations and optimized conditions for growth and harvest

**units were converted based on the average TSP values obtained with the respective extraction method [10]