Table 1.
Biological sample | Model | eCB alterations | Reference |
---|---|---|---|
Postmortem brain | Human | ↓CB1 | [121] |
PBMCs | Human | ↓NAPE–PLD mRNA = FAAH, CB1 mRNA ↑CB2 mRNA and protein |
[107] |
Saliva | Human | CB1 SNP | [116, 119] |
PBMCs = peripheral blood mononuclear cells; CB1 = type-1 cannabinoid receptor; NAPE–PLD = N-acylphosphatidyl-ethanolamine-specific phospholipase D; FAAH = fatty acid hydrolase; CB2 = type-2 cannabinoid receptor; SNP = single nucleotide polymorphism