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. 2015 Oct 13;10(10):e0140475. doi: 10.1371/journal.pone.0140475

Table 1. Different data for the biochemical compounds.

No. of patients Reference interval MAB (≤1/3×SDpop)
TSH 19,180 20+ years, 0.30–4.0 mIU/L 0.31
Calcium 13,588 2,15–2,51 mmol/L 0.03
Sodium 51,917 137–145 mmol/L 0.67
Albumin 42,399/15,544* 15–40 years, 36–50 g/L 1.17**
- 40–70 years, 36–48 g/L -
- 70+ years, 34–45 g/L -

* 0–10 minutes resting time (both numbers includes all patients above the age of 15)

** calculated from a compromise between the three reference intervals

The maximum allowable bias (MAB) indicates the largest difference from the reference interval that is allowed. If the difference exceeds this value, the reference interval is no longer valid. For albumin only values from patients who waited 0–10 minutes (n = 15,544) are used for the linear regression, since the entire change occurred within this time interval.