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Probability of target attainment (PTA) versus MIC for different dosing regimens and modes of administration, for the first day of piperacillin treatment. Calculations were done based on 1,000 simulations of PK in the population using the final model. IA, intermittent bolus administration; EI, extended infusion; CI, continuous infusion. The dotted black lines represent a PTA of 90%.
