TABLE 3.
Percentage of time above MIC (% T>MIC) and PK/PD target achievement for pathogens actually detected (n = 7)a
| Patient and pathogen (MIC, mg/liter) | PK/PD target |
|||
|---|---|---|---|---|
| % T>4×MIC | Target achieved | % T>MIC | Target achieved | |
| Patient 1, E. coli (1.5) | 100 | Yes | 100 | Yes |
| Patient 8, E. coli (64) | 18 | No | 100 | Yes |
| Patient 10, E. coli (2) | 52 | Yes | 74 | No |
| Patient 15 | ||||
| S. pneumoniae (0.016) | 100 | Yes | 100 | Yes |
| S. aureus (0.5) | 100 | Yes | 100 | Yes |
| E. faecalis (3) | 64 | Yes | 93 | No |
| K. oxytoca (256) | 0 | No | 7 | No |
a
For each pathogen, the model-predicted % T>MIC for that particular individual was calculated.