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. 2015 Oct 13;59(11):7018–7026. doi: 10.1128/AAC.01347-15

TABLE 4.

Estimates of percentage of time above MIC, derived from predictions of alternative dosing regimens

Mode of administration T>MICa (%) at first dose for patient with PK profile, by dose per 24 h
Population avg
 Low
16 g 12 g 8 g 16 g 12 g 8 g
IA 100 100 84 54 40 27
EI 98 100 98 82 70 58
CI 100 100 100 100 100 54
a

EUCAST clinical breakpoint MIC for P. aeruginosa (16 mg/liter).