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Competition experiments between E. coli B cells expressing single mutant and double mutant variants of CTX-M-14. (A) Competition experiments between P167S and A77V/P167S in the presence of increasing concentrations of cefotaxime (left panel) and ceftazidime (right panel). (B) Competition experiments between D240G and A77V/D240G with increasing concentrations of cefotaxime (left panel) and ceftazidime (right panel).
