TABLE 5.
Thermal stabilities of CTX-M variants
| WT or mutant β-lactamase | Tm (°C) | ΔTm (°C) |
|---|---|---|
| CTX-M-14 | 54.0 ± 0.09 | |
| A77V | 57.3 ± 0.14 | +3.3 |
| P167S | 51.8 ± 0.16 | −2.2 |
| D240G | 53.6 ± 0.08 | −0.4 |
| A77V/P167S | 52.3 ± 0.12 | −1.7 |
| A77V/D240G | 56.8 ± 0.08 | +2.8 |
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