FIG 1.

MycoTB plate with proportions of isolates (percentages in bold) distributed at each MIC. Colors indicate the following: green, susceptible; yellow, borderline; red, resistant. Borderline shading is plus or minus one dilution around the agar proportion breakpoint for medications where a dose increase could be tried or for cycloserine where the dose could be reduced when an isolate is highly susceptible. The squares with solid blue outlines are the susceptibility breakpoints by agar proportion, and a narrow rectangle is drawn when this breakpoint falls between the recorded MICs (for ethambutol and cycloserine). The square with a dashed blue outline represents the proposed breakpoint for moxifloxacin according to Lee et al. (7). The solid black circles cover breakpoints by the MGIT 960. OFX, ofloxacin; MFX, moxifloxacin; RIF, rifampin; AMI, amikacin; STR, streptomycin; RFB, rifabutin; PAS, p-aminosalicylic acid; ETH, ethionamide; CYC, cycloserine; INH, isoniazid; KAN, kanamycin; EMB, ethambutol.