FIG 1.

Comparison of ring-stage parasite survival rates with in vivo parasite clearance and K13 genotypes. Ring-stage survival rates of the culture-adapted parasites measured by the RSA were compared between day 3 parasite-positive and -negative samples, between parasites with and without the NN insertion at the N terminus, and between parasites with and without mutations in the K13 propeller domain. Wild-type (WT) parasites are shown as open circles, whereas parasites carrying K13 mutations are color coded. Statistical analysis was performed using a Mann-Whitney U test, and P values are shown.