TABLE 1.
Strain | MIC (μg/ml) |
Sequencing platform | Rv2887 mutation | |
---|---|---|---|---|
MP-III-71 | Complement MP-III-71 | |||
H37Rv | 0.25–0.5 | SOLiD and PGM | ||
Mutant 1 | 2 | 0.25–0.5 | PGM | Deletion at positions 3194362–3197545 (3,183 bp), which includes Rv2885c, Rv2886c, Rv2887, and Rv2888c |
Mutant 2 | 1–2 | 0.25–0.5 | PGM | 2-bp deletion at positions 3196830–3196831, which is nucleotide 399 in Rv2887 (amino acid 133) |
Mutant 3 | 1 | 0.25–0.5 | SOLiD | V61A nonsynonymous SNP in Rv2887 |