TABLE 3.

Cell extraction efficiency of atazanavir, ritonavir, and tenofovir

Parameter	Data for drugs by concentration (ng/106 cells)
	Atazanavir			Ritonavir			Tenofovir
	0.5	5	10	0.5	5	10	0.5	5	10
Calculated concn (ng/106 cells) for run:
1	0.47	4.63	8.62	0.43	4.11	9.12	0.49	4.61	8.50
2	0.49	4.76	8.71	0.45	4.01	8.67	0.51	4.65	9.72
3	0.55	4.83	9.22	0.48	4.06	8.87	0.50	4.64	8.76
4	0.58	4.61	8.60	0.44	4.47	8.77	0.50	4.77	8.83
5	0.51	4.71	8.97	0.49	4.60	9.06	0.50	4.84	8.63
6	0.57	4.90	8.79	0.44	4.57	9.09	0.51	4.96	8.89
Avg concn (ng/106 cells)	0.53	4.74	8.81	0.46	4.31	8.93	0.50	4.74	8.89
SD	0.04	0.11	0.25	0.02	0.27	0.18	0.01	0.14	0.43
%CV	8.33	2.32	2.78	5.22	6.35	2.07	0.91	2.88	4.86
% recovery	105.63	94.80	88.09	91.43	86.10	89.30	100.57	94.89	88.89

^aValues are given as calculated concentrations, with spiked extracted blank plasma representing 100%.