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Population pharmacokinetic model of emtricitabine in blood plasma and seminal plasma. The parameters of this model are the absorption rate constant (ka), apparent elimination clearance (CL/F), central volume of distribution (Vc/F), intercompartmental clearance (Q/F), peripheral volume of distribution (Vp/F), blood plasma-to-seminal plasma transfer (k1e), and seminal plasma elimination rate constants (ke1), with F being unknown bioavailability.
