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. 2015 Oct 14;5:13872. doi: 10.1038/srep13872

Figure 1. Schematic overview of all Hepatitis E virus ORFs and ORF subdomains.

Figure 1

Bars indicate defined domains: Met: Methyltransferase; Y: Y-domain; Plp: Papain like protease; V: variable region (poly-proline-hinge); X: X-domain (macro-domain); Pvx: Protein consisting of the domains Plp, V and X; Hel: Helicase; Rdrp: RNA dependent RNA polymerase; O3: ORF3 protein; O2: ORF2 protein (capsid); O2_FLd: Full length delta; O2_S: shell domain; O2_P1: protruding domain 1; O2_P2: protruding domain 2; Nucleotide (nt) numbers indicating position in the sequence (adapted from Osterman et al.54).