Figure 2. Effect of TLR9, TLR7 and TLR3 agonists on the titer of polyreactive antibodies.

Two to four months old C57BL/6 mice were injected with TLR ligands (A) CpG; (B) Imiquimod; (C) Poly (I:C) and polyreactive antibody titers in the sera were assessed at the indicated time points. Data represents Mean ± SEM (n = 5 mice per group, ANOVA) from two independent experiments.