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. 2015 Oct 14;5:15031. doi: 10.1038/srep15031

Figure 6. Expression of N-WASP-I30 rescued the defective chemotaxis of WASPKD Jurkat T cells.

Figure 6

(A) Expression levels of His tagged WASPR and N-WASP, N-WASP-I30 and vector alone in JurkatWKD T-cells. (B) Vector plots representing the migration path of JurkatWKD T-cells expressing (1) WASPR-His, (2) N-WASP-His, (3) N-WASP-I30-His in Dunn chamber assay. (C) Migration velocity of total 60 randomly selected cells of cell type as in panel B. *P < 0.05, **P < 0.01 compared to vector expressing JurkatWKD T-cells. (D) Overall directionality of JurkatWKD T-cells expressing plasmid as in panel B. (E) Transwell migration of JurkatWKD T-cells expressing (1) WASPR-His, (2) N-WASP-His, (3) N-WASP-I30-His. **P < 0.01 compared to vector expressing JurkatWKD T-cells.