Figure 8. Effect of capillary water secretion rate on the water flow rate through inter-endfeet gaps connecting the perivascular AUs to the (a) arterial and (b) venous PVS, respectively.

The left most pair of bars in both panels show values for zero water secretion, whereas the right most pairs bars give the values for the case where all of the water inflow into the domain stems from capillary secretion. The white bars represent the AQP4 deletion state, in which next to the removal of the corresponding pathway in the AUs, a reduction of the capillary water secretion by 31% is imposed²².