Table 2.
Multiple regression analysis
| Factor | Degree of freedom | Sum of squares | F value | P value |
|---|---|---|---|---|
| PGAs | 3 | 106.7065789 | 8.26 | <0.0001 |
| Age | 1 | 1.1326213 | 0.26 | 0.6089 |
| Sex | 1 | 5.9941339 | 1.39 | 0.2402 |
| Dosing period of PGAs | 1 | 0.0018124 | 0.00 | 0.9837 |
| Baseline intraocular pressure | 1 | 68.9170780 | 16.00 | 0.0001 |
| Baseline MD value | 1 | 6.8635484 | 1.59 | 0.2090 |
| Baseline PSD value | 1 | 11.7128012 | 2.72 | 0.1014 |
MD mean deviation, PGAs prostaglandin analogs, PSD pattern standard deviation
In a multiple regression analysis with IOP reduction from baseline at 12 weeks after switching to Duotrav as a dependent variable, and demographic and baseline characteristics as independent variables, the type of PGA used in prior treatment and baseline IOP had a significant association. Coefficient of determination [R 2] was 0.29