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. 2015 Oct 14;5:14986. doi: 10.1038/srep14986

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(a) The cytotoxic effects on C32 human melanoma cells after incubation of PEI and CNPs for 48 hr. (b) Immunotoxic assessment of complement activation resulted from 4, 8, 16, 32 and 64 times dilutions of swine plasma. (c) Change in chemistry of 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide after cellular reduction in living cells. Formazan concentration correlates with viable cell population among treated pool of cells. (d) Comparative evaluation of IC50 values related to hydrodynamic diameters and surface zeta potential of various nanoparticles.