Table 2.
Comparison of characteristics and outcomes of conventional and delayed start COS cycles
| Conventional Start (n=9) |
Delayed Start (n=9) |
Between-group difference (95% confidence interval) |
p value |
|
|---|---|---|---|---|
| Days of ovarian stimulation | 11.1 ± 2.0 | 9.4 ± 1.4 | − 1.7 (−3.1, −0.3) | 0.024 |
| Total dose of gonadotropins (IU) | 5000 ± 884 | 4250 ± 641 | −750 (−1374, −126) | 0.024 |
| Endometrial thickness (mm) | 9.5 ± 2.2 | 10.9 ± 2.5 | 1.4 (−0.2, 3.1) | 0.082 |
| Follicles ≥ 13 mm | 3.9 ± 1.3 | 6.7 ± 2.2 | 2.8 (1.3, 4.3) | 0.002 |
| Oocytes retrieved | 4.3 ± 1.8 | 6.6 ± 2.6 | 2.3 (0.13, 4.3) | 0.04 |
| Mature oocytes (MII) retrieved | 2.2 ± 1.1 | 4.9 ± 2.0 | 2.7 (1.1, 4.2) | 0.004 |
| MII oocyte / total oocytes ratio | 0.53 ± 0.20 | 0.73 ± 0.10 | 0.20 (0.01, 0.4) | 0.041 |
| Oocyte / AFC ratio | 0.76 ± 0.36 | 1.13 ± 0.21 | 0.37 (0.06, 0.68) | 0.024 |
| Mature oocyte / AFC ratio | 0.38 ± 0.19 | 0.86 ± 0.21 | 0.48 (0.24, 0.72) | 0.003 |
| Fertilization rate after ICSI (2PN/MII) | 0.69 ± 0.21 | 0.86 ± 0.17 | 0.17 (−0.10, 0.44) | 0.17 |
| Day of transfer | ||||
| Day 2 | 8 (100%)a | 6 (67%) | ||
| Day 3 | 0 | 3 (33%) | ||
| Embryos Transferred | 1.6 ± 1.2 | 3.4 ± 1.6 | 1.8 (0.5, 3.0) | 0.013 |
| Implantation Rate | 0 | 6.5 % | ||
| Clinical Pregnancy Rate | 0 | 2 (22.2%) |
a
One patient did not have any viable oocyte at the time of retrieval