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. 2015 Oct 13;11:64. doi: 10.1186/s12990-015-0067-5

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© Betelli et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Glycine receptors do not contribute to presynaptic inhibition of transmitter release. a Example of the effects of 300 nM strychnine and strychnine plus 10 μM gabazine on a train of four eEPSCs recorded from a lamina III/IV neuron (averaged eEPSCs from 5 to 6 consecutive traces in each condition). b Mean EPSC peak amplitudes in control, strychnine and strychnine plus gabazine are plotted for each of the four synaptic events, from a sample of seven lamina III/IV neurons. While strychnine alone is not effective, addition of gabazine causes a significant increase of the second peak (repeated measures ANOVA, Tukey post-test, p < 0.05, n = 7). c The increase of the eEPSC second peak in gabazine is related to PPR_ctl, as shown in Fig. 3